Thiazolo[5,4-b]pyridin-2-amine, 5-bromo-

Thiazolo[5,4-b]pyridin-2-amine, 5-bromo- - Names and Identifiers

Name	5-bromothiazolo[5,4-b]pyridin-2-amine
Synonyms	5-bromothiazolo[5,4-b]pyridin-2-amine 2-AMINO-5-BROMOTHIAZOLO[5,4-B]PYRIDINE Thiazolo[5,4-b]pyridin-2-amine, 5-bromo- 5-BroMo-thiazolo[5,4-b]pyridin-2-ylaMine 5-broMo-[1,3]thiazolo[5,4-b]pyridin-2-aMine 5-Bromo [1,3]thiazolo[5,4-b]pyridine-2-amine
CAS	934266-82-7
InChI	InChI=1/C6H4BrN3S/c7-4-2-1-3-5(10-4)11-6(8)9-3/h1-2H,(H2,8,9)

Thiazolo[5,4-b]pyridin-2-amine, 5-bromo- - Physico-chemical Properties

Molecular Formula	C6H4BrN3S
Molar Mass	230.09
Density	1.950±0.06 g/cm3(Predicted)
Boling Point	382.6±45.0 °C(Predicted)
pKa	0.74±0.40(Predicted)
Storage Condition	2-8℃
Refractive Index	1.803

Thiazolo[5,4-b]pyridin-2-amine, 5-bromo- - Introduction

5-bromothiazolo[5,4-b]pyridin-2-amine is an organic compound with the chemical formula C6H4BrN3S. The following is a detailed description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: 5-bromothiazolo[5,4-b]pyridin-2-amine is a white to light yellow solid.
-Solubility: Soluble in some organic solvents, such as dichloromethane, dimethyl sulfoxide and dimethylformamide, but insoluble in water.
-Melting point: approximately 132-134°C.

Use:
- 5-bromothiazolo[5,4-b]pyridin-2-amine is commonly used as an intermediate in organic synthesis and an important raw material for drug synthesis.
-It can be used to prepare other organic compounds, such as biologically active natural products or pharmaceutical compounds.

Method:
- 5-bromothiazolo[5,4-b]pyridin-2-amine can be prepared by the reaction of thiazole and bromide.
-A common preparation method is to react thiazole and bromopyridine, and complete the reaction in the presence of a base to obtain the desired product.

Safety Information:
- 5-bromothiazolo[5,4-b]pyridin-2-amine has low toxicity under general use.
-When using or handling the compound, appropriate laboratory safety measures should be taken, including wearing chemical protective gloves and goggles.
-The compound should also be stored properly, taking care to avoid contact with oxygen, strong oxidants or other flammable substances.

Please note that this information is for informational purposes only, and specific experimental procedures and safety measures may vary depending on the specific situation. For practical applications, refer to the relevant literature or consult an experienced chemist.

Last Update：2024-04-09 15:18:00